Publications
2017
- Improvement of In Vivo Expression of Genes Delivered by Self-Amplifying RNA Using Vaccinia Virus Immune Evasion ProteinsTim Beissert, Lars Koste, Mario Perkovic, Kerstin C. Walzer, Stephanie Erbar, Abderraouf Selmi, Mustafa Diken, Sebastian Kreiter, Özlem Türeci & Ugur Sahindoi: 10.1089/hum.2017.121
2018
- Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower DosesAnnette B. Vogel, Laura Lambert, Ekaterina Kinnear, David Busse, Stephanie Erbar, Kerstin C. Reuter, Lena Wicke, Mario Perkovic, Tim Beissert, Heinrich Haas, Stephen T. Reece, Ugur Sahin & John S. Tregoningdoi: 10.1016/j.ymthe.2017.11.017
- Production of RNA by yeasts with recombinant pseudo-viral particlesLucie Pigeon, Rachid Rahmouni, Chantal Rabenadrasana-Pichon & Patrick Midoux WO2018/171946 A1
- Cholinium-based Good’s buffers ionic liquids as remarkable stabilizers and recyclable preservation media for recombinant small RNAsAugusto Q. Pedro, Patrícia Pereira, Maria J. Quental, André P. Carvalho, Sérgio M. Santos, João A. Queiroz, Fani Sousa & Mara G. Freiredoi: 10.1021/acssuschemeng.8b03900
2019
- Integrated Extraction-Preservation Strategies for RNA Using Biobased Ionic LiquidsMaria J. Quental, Augusto Q. Pedro, Patrícia Pereira, Mukesh Sharma, João A. Queiroz, João A. P. Coutinho, Fani Sousa & Mara G. Freiredoi: 10.1021/acssuschemeng.9b00688
2020
- A Trans-amplifying RNA Vaccine Strategy for Induction of Potent Protective ImmunityTim Beissert, Mario Perkovic, Annette Vogel, Stephanie Erbar, Kerstin C. Walzer, Tina Hempel, Silke Brill, Erik Haefner, René Becker, Özlem Türeci & Ugur Sahindoi: 10.1016/j.ymthe.2019.09.009
- mRNA with Mammalian Codon Bias Accumulates in Yeast Mutants with Constitutive Stress GranulesNatalia V. Kozlova, Chantal Pichon & A. Rachid Rahmounidoi: 10.3390/ijms21041234
- Two new capture options for improved purification of large mRNAPete Gagnon, Blaž Goričar, Špela Peršič, Urh Černigoj & Aleš Štrancardoi: 10.18609/cgti.2020.114
- Improved ionic-liquid-functionalized macroporous supports able to purify nucleic acids in one stepM.C. Neves, P. Pereira, A.Q. Pedro, J.C. Martins, T. Trindade, J.A. Queiroz, M.G. Freire & F. Sousadoi: 10.1016/j.mtbio.2020.100086
2021
- Eliminating the Analytical Bottleneck in Production and Purification of mRNATomas Kostelec, Rok Sekirnik, Anže Martinčič Celjar, Kristina Šprinzar Nemec, Andreja Gramc Livk, Pete Gagnon & Aleš Štrancar
- Chromatographic purification with CIMmultus™ Oligo dT increases mRNA stabilityMatevž Korenč, Nina Mencin, Jasmina Puc, Janja Skok, Kristina Šprinzar Nemec, Anže Martinčič Celjar, Pete Gagnon, Aleš Štrancar & Rok Sekirnikdoi: 10.18609/cgti.2021.161
- mRNA, a Revolution in BiomedicineBruno Baptista, Rita Carapito, Nabila Laroui, Chantal Pichon & Fani Sousadoi: 10.3390/pharmaceutics13122090
2023
- Development and scale-up of oligo-dT monolithic chromatographic column for mRNA capture through understanding of base-pairing interactionsNina Mencin, Dona Stepec, Alja Margon, Jana Vidic, Darko Dolenc, Tina Simcic, Sara Rotar, Rok Sekirnik, Ales Strancar & Urh Cernigojdoi: 10.1016/j.seppur.2022.122320
- High Recovery Chromatographic Purification of mRNA at Room Temperature and Neutral pHRok Miklavčič, Polona Megušar, Špela Meta Kodermac, Blaž Bakalar, Darko Dolenc, Rok Sekirnik, Aleš Štrancar & Urh Černigojdoi: 10.3390/ijms241814267
- Scalable multimodal weak anion exchange chromatographic purification for stable mRNA drug substancePolona Megušar, Rok Miklavčič, Matevž Korenč, Jure Ličen, Tina Vodopivec, Urh Černigoj, Aleš Štrancar & Rok Sekirnikdoi: 10.1002/elps.202300106