Yeast cell factory for mRNA bioproduction
Logo of Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz gemeinnützige GmbH

Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz gemeinnützige GmbH

TRON is an independent non-profit translational research organization that develops highly innovative technologies to target diseases with high medical needs such as infectious diseases, autoimmunity and cancer. TRON was founded in 2010 and has already played a transformative role in global health challenges and applied science. Located in the research hub Mainz, our institute has strong ties to both academia and industry and is characterized by a vibrant, cutting-edge and creative research environment, a flat hierarchy and an international and diverse work force. We combine our transdisciplinary competencies in genomics and immunology to develop novel platforms for the identification and validation of ‘omics’-based biomarkers to harness and modulate immune system components for the use in personalized therapies. Several TRON inventions have already found their way into clinical trials. Collaborating with academia and industry, TRON executes research at the leading edge to support innovative drug design for human health.

Role within Yscript

TRON gGmbH (Germany) brings extensive expertise in engineering mRNA for therapies and vaccines to optimise the features of mRNA produced in yeast (Work package 1). In addition, TRON leads the Quality Control and biological validation of bio-produced mRNA (Work package 4).

Our vision for Yscript

Humanity has been using yeast for producing bread and beer before even knowing that it exists. Now we use yeast on purpose for the latest class of pharmacological substances. We are thrilled to be part of this vision.

Main contacts

Photo of Mario Perkovic
Mario Perkovic

Work Package 4 Lead

Photo of Tim Beissert
Tim Beissert
Photo of Marijn van Jaarsveld
Marijn van Jaarsveld

Project Manager, Communications